• Inbiolabs offers medium throughput compound screening in a number of normal and tumour cell lines
• Inbiolabs services provide highly reproducible results and can be used as a stand-alone activity or in support of a wider programme

In vitro research and development services:

DNA CLONING & PROTEIN PRODUCTION
Production of up to 10 mg of protein in bacterial system. Includes: best clone screen, induction optimisation, solubility study,  purification from inclusion bodies, gel filtration chromatography, endotoxin removal.

CYTOTOXICITY AND CELL PROLIFERATION ASSAYS
-Cell cycle analysis using the flow cytometric bromodeoxyuridine (BrdU) incororation method
-MTT and LDH release assays for cell viability testing 

APOPTOSIS ASSAYS
-Annexin binding assay, providing an early indication of apoptosis.
-TUNEL or DNA fragmentation assay, for detecting late phase apoptosis

RADIOLIGAND BINDING ASSAYS
-Saturation analysis: receptor affinity (Kd) and density (Bmax) can be determined in both cell membrane and whole cell systems
-Competition analysis: determining equilibrium dissociation constant (Ki)

CELL MIGRATION ASSAY
Cell Migration Assay is designed to study the effects of various drugs or agents on cell motility and to identify chemoattractant molecules.